Fig. 6
From: MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B
MiR-93-5p inhibitor promotes dentin formation in pulpotomy model. A MicroCT showed that KDM6B-overexpression and miR-93-5p inhibitor induced tertiary dentin formation in rat pulpotomy model after 4Â weeks treatment (yellow arrows: tertiary dentin). B, C Immunofluorescence staining showed that KDM6B was upregulated while H3K27me3 marks were downregulated after miR-93-5p inhibitor or KDM6B-overexpression treatment (TD: tertiary dentin, NT: necrosis tissues, red arrows: positive cells). D H&E staining illustrated the tertiary dentin over the opening of tooth root canals (green arrows: odontoblasts)