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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B

Fig. 5

MiR-93-5p influences the KDM6B and H3K27me3 affinity on BMP2 gene. A–C MiR-93-5p mimic treatment reduced the KDM6B affinity in promoter regions of BMP2, OSX and OCN, respectively. D MiR-93-5p mimic treatment increased the H3K27me3 marks in BMP2 promoter regions. E, F MiR-93-5p mimic treatment had no significant effects on H3K27me3 marks in promoter regions of OSX and OCN. ns, not significant. *P < 0.05, **P < 0.01 and ***P < 0.001

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