Fig. 3
From: MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B
Downregulation of miR-93-5p promotes the odontogenic differentiation of hDPSCs. A The miR-93-5p inhibitor was effectively transfected into hDPSCs. B MiR-93-5p inhibitor increased the ALP activity of hDPSCs during odontogenic differentiation. C MiR-93-5p inhibitor induced mineralized nodule formation during the odontogenic differentiation of hDPSCs. D–G MiR-93-5p inhibitor increased the mineralization indicators genes OSX, ALP, OCN and COL-1α when hDPSCs differentiated into odontoblasts. ns, not significant. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001