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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B

Fig. 2

Upregulation of miR-93-5p suppresses the odontogenic differentiation of hDPSCs. A The miR-93-5p mimic was effectively transfected into hDPSCs. B MiR-93-5p mimic suppressed the ALP activity of hDPSCs during odontogenic differentiation. C MiR-93-5p mimic suppressed the mineralized nodule formation during the odontogenic differentiation of hDPSCs. D–G MiR-93-5p mimic decreased the mineralization indicators genes OSX, ALP, OCN and COL-1α when hDPSCs differentiated into odontoblasts. ns, not significant. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001

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