Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: A novel biomarker associated with EBV infection improves response prediction of immunotherapy in gastric cancer

Fig. 2

EBV infection and CHAF1A mRNA expression. A: CHAF1A mRNA expression according to EBV infection status. B: The ROC curve for EBV infection prediction by CHAF1A mRNA expression. C: Positive rate of EBV infection according to CHAF1A expression level. Based on the optimal threshold of CHAF1A expression for the maximum ROC curve values, the patients are dichotomized into high and low subgroups. D: EBV + HGC (HGC-EBV) cells (reddish brown) detected by EBER after co-culture of HGC with B95-8 cells (removed). E: HGC-EBV cells express BamHI-W mRNA which is exclusively expressed by EBV + cells. F: HGC-EBV cells do not express CAJA-DRB1 mRNA which is exclusively expressed by marmoset cells, indicating that the B95-8 cells have been removed. G: EBV infection improves CHAF1A mRNA expression. AHJU Affiliated Hospital of Jiangsu University, ROC receiver operating characteristic curve, AUC the areas under the ROC curves

Back to article page