Fig. 1

Selection of EBV-associated genes. A: Volcano plot for differentially expressed genes (DEGs) between EBV- and EBV + GC in the TCGA cohort. B: Heatmap of the TOP 40 DEGs. C: Prognostic DEGs in both the ACRG and TCGA GC cohorts. D: Average functional similarities between the gene and its interaction partners according to their semantic similarities of Gene Ontology terms for molecular function. E: CHAF1A mRNA expression is an independent predictor of overall survival in both the TCGA and ACRG cohorts. GC gastric cancer, ACRG Asian Cancer Research Group, TCGA The Cancer Genome Atlas