Fig. 6
From: DEL-1: a promising treatment for AMD-associated ER stress in retinal pigment epithelial cells
DEL-1 attenuates ER stress and apoptosis in primary hRPE cells. A Western blot analysis depicting phosphorylated eIF2α and CHOP in primary hRPE cells treated with tunicamycin (1 μg/mL) and/or DEL-1 (0–1 μg/mL) for 24 h. B Cell viability and caspase 3 activity assay in primary hRPE cells treated with tunicamycin (2 μg/mL) and/or DEL-1 (0–1 μg/mL) for 24 h. Means ± SDs were calculated from three independent experiments in in vitro models. *P < 0.05 compared with the control. !P < 0.05 compared with tunicamycin (1 or 2 μg/mL) treatment