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Table 4 Simple correlations among the Sartorius scores and changes in the study parameters after 28 days of the active phase of VLCKD

From: Very low-calorie ketogenic diet (VLCKD) in the management of hidradenitis suppurativa (Acne Inversa): an effective and safe tool for improvement of the clinical severity of disease. Results of a pilot study

Δ%

Δ% Sartorius score

Simple Correlation

r

p-value

Anthropometric parameters

 Weight (kg)

0.038

0.908

 BMI (kg/m2)

0.035

0.914

 WC (cm)

− 0.211

0.510

BIA parameters

 R (Ω)

0.312

0.323

 Xc (Ω)

− 0.896

 < 0.001

 Na/K

− 0.149

0.643

 BCM (kg)

− 0.839

0.001

 TBW (%)

− 0.679

0.015

 ECW (%)

0.973

 < 0.001

 ICW (%)

− 0.951

 < 0.001

 FM (kg)

0.607

0.036

 FM (%)

0.627

0.029

 FFM (kg)

− 0.691

0.013

 FFM (%)

− 0.680

0.015

 MM (kg)

− 0.711

0.009

 MM (%)

− 0.707

0.010

 BCMI (kg/m2)

− 0.243

0.447

 PhA (°)

− 0.953

 < 0.001

Biochemical parameters

 Fasting plasma glucose (mg/dl)

0.192

0.571

 Insulin (μU/ml)

0.396

0.257

 HoMA-IR

0.353

0.317

 Total cholesterol (mg/dL)

− 0.266

0.429

 HDL cholesterol (mg/dL)

− 0.129

0.706

 LDL cholesterol (mg/dL)

− 0.149

0.662

 Triglycerides (mg/dL)

− 0.281

0.402

 Azotemia (mg/dL)

− 0.302

0.340

 Creatinemia (mg/dL)

− 0.024

0.941

 Uricemia (mg/dL)

− 0.291

0.358

 AST (U/L)

0.519

0.084

 ALT (U/L)

0.326

0.301

 γGT (U/L)

0.020

0.951

 ESR (mm/h)

0.314

0.410

 Sodiemia (mmol/l)

0.152

0.637

 Potassiema (mmol/l)

0.217

0.497

Dermatological parameter

 DLQI score

− 0.170

0.596

Inflammation and oxidative stress parameters

 Ox-LDL (μg/mL)

0.796

0.002

 dROMs (U Carr)

0.953

 < 0.001

 TMAO (µM)

0.936

 < 0.001

  1. A p-value in bold type denotes a significant difference (p < 0.05). Δ%, percentage change; BMI body mass index, WC waist circumference, BIA body impedance analysis, R resistance, Xc reactance, BCM body cell mass, TBW total body water, ECW extracellular water, ICW intracellular water, FM fat mass, FFM fat free mass, MM muscle mass, BCMI body cell mass index, PhA phase angle, HoMA-IR homeostatic model for assessment of insulin resistance, HDL high density lipoprotein, LDL, low density lipoprotein, AST, aspartate transaminase, ALT alanine transaminase; γGT, γglutamyltransferase; ESR, erythrocyte sedimentation rate; DLQI, dermatology life quality index; ox-LDL, oxidized low-density lipoprotein; dROMS, reactive oxygen metabolites, TMAO trimethylamine n-oxide