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Table 2 Biochemical parameters of the study population at baseline and after 28 days of the active phase of VLCKD

From: Very low-calorie ketogenic diet (VLCKD) in the management of hidradenitis suppurativa (Acne Inversa): an effective and safe tool for improvement of the clinical severity of disease. Results of a pilot study

Parameters (N = 12)

Baseline

Day 28 of VLCKD

p-value

Δ %

Fasting plasma glucose (mg/dL)

88.82 ± 7.95

80.64 ± 8.76

0.084

− 8.15 ± 15.73

Insulin (μU/mL)

12.48 ± 6.68

9.88 ± 6.60

0.218

− 16.70 ± 47.24

HoMA− IR

2.71 ± 1.50

2.09 ± 1.55

0.248

− 17.93 ± 55.15

Total cholesterol (mg/dL)

184.73 ± 26.01

147.55 ± 30.62

0.002

− 19.41 ± 15.19

HDL cholesterol (mg/dL)

61.22 ± 11.37

53.04 ± 13.86

0.002

− 14.02 ± 12.23

LDL cholesterol (mg/dL)

103.38 ± 24.50

77.13 ± 20.05

0.003

− 23.16 ± 18.82

Triglycerides (mg/dL)

102.36 ± 57.58

82.82 ± 32.12

0.223

− 7.77 ± 32.07

Azotemia (mg/dL)

32.00 ± 9.38

28.50 ± 9.95

0.158

− 9.33 ± 21.96

Creatinemia (mg/dL)

0.76 ± 0.17

0.75 ± 0.12

0.777

0.59 ± 14.50

Uricemia (mg/dL)

4.93 ± 0.92

5.39 ± 1.13

0.197

10.58 ± 22.13

AST (U/L)

25.50 ± 10.82

24.17 ± 10.67

0.258

− 3.80 ± 15.68

ALT (U/L)

29.67 ± 19.13

25.58 ± 18.34

0.055

− 11.68 ± 21.10

γGT (U/L)

15.92 ± 4.72

13.92 ± 4.25

0.074

− 10.60 ± 21.48

ESR (mm/h)

28.44 ± 15.21

22.44 ± 18.25

0.307

− 18.30 ± 47.46

Sodiemia (mmol/L)

4.30 ± 0.27

4.33 ± 0.37

0.591

0.31 ± 1.89

Potassiema (mmol/L)

4.30 ± 0.27

4.33 ± 0–37

0.700

0.44 ± 4.49

  1. A p-value in bold type denotes a significant difference (p < 0.05). VLCKD, very low-calorie ketogenic diet; Δ%, percentage change; HoMA-IR, homeostatic model for assessment of insulin resistance; HDL, high density lipoprotein, LDL low density lipoprotein, AST aspartate transaminase, ALT alanine transaminase, γGT γglutamyltransferase, ESR erythrocyte sedimentation rate