Very low-calorie ketogenic diet (VLCKD) in the management of hidradenitis suppurativa (Acne Inversa): an effective and safe tool for improvement of the clinical severity of disease. Results of a pilot study

Table 1 Anthropometric characteristics and body composition of the study population at baseline and after 28 days of the active phase of VLCKD

Parameters (N = 12)	Baseline	Day 28 of VLCKD	p-value	Δ %
Anthropometric parameters
Weight (kg)	101.43 ± 14.52	93.51 ± 14.77	< 0.001	− 7.94 ± 1.95
BMI (kg/m²)	35.95 ± 5.89	33.15 ± 5.88	< 0.001	− 7.94 ± 1.95
WC (cm)	109.5 ± 17.34	100.92 ± 15.66	0.002	− 7.56 ± 6.34
BIA parameters
R (Ω)	493.25 ± 46.59	469.67 ± 40.30	0.003	− 4.61 ± 4.04
Xc (Ω)	50.83 ± 4.59	56.25 ± 7.46	0.002	10.45 ± 9.28
Na/K	0.87 ± 0.14	0.86 ± 0.14	0.754	− 0.51 ± 9.91
BCM (kg)	29.97 ± 4.01	32.83 ± 3.68	0.026	10.56 ± 14.26
TBW (%)	41.50 ± 5.16	45.76 ± 7.04	0.005	10.25 ± 9.92
ECW (%)	46.26 ± 3.58	42.34 ± 3.43	< 0.001	− 8.35 ± 5.12
ICW (%)	53.74 ± 3.58	57.66 ± 3.43	< 0.001	7.41 ± 4.59
FM (kg)	45.19 ± 13.24	36.49 ± 14.77	< 0.001	− 21.01 ± 13.80
FM (%)	43.89 ± 6.59	37.85 ± 9.38	0.004	− 14.26 ± 14.32
FFM (kg)	56.23 ± 4.99	57.02 ± 3.66	0.580	1.90 ± 8.90
FFM (%)	56.12 ± 6.59	62.15 ± 9.38	0.004	10.72 ± 9.87
MM (kg)	25.96 ± 3.81	27.13 ± 2.64	0.268	5.95 ± 15.02
MM (%)	25.96 ± 4.70	29.76 ± 5.92	0.009	15.25 ± 16.56
BCMI	10.63 ± 1.60	11.56 ± 1.37	0.001	9.48 ± 7.92
PhA (°)	5.93 ± 0.77	6.83 ± 0.80	< 0.001	15.54 ± 10.43

A p–value in bold type denotes a significant difference (p < 0.05). VLCKD, very low-calorie ketogenic diet; Δ%, percentage change; BMI body mass index, WC waist circumference, BIA body impedance analysis, R resistance, Xc reactance, BCM body cell mass, TBW total body water, ECW extracellular water, ICW intracellular water, FM fat mass, FFM fat free mass, MM muscle mass, BCMI body cell mass index, PhA phase angle

ISSN: 1479-5876