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Table 2 Information on immune repertoire sequencing and analysis

From: The spike-specific TCRβ repertoire shows distinct features in unvaccinated or vaccinated patients with SARS-CoV-2 infection

Patient ID

n_sequence

pre-stimul

n_clna

pre-stimul

n_sequence post-stimul

n_cln post-stimul

cln in MIRAb

Spike_seq% (pre)c

Spike_seq% (post) c

NV1

247282

6409

383272

7742

354

0.0569

0.3942

NV2

273882

5729

323193

5818

151

0.0157

0.1695

NV3

261658

819

265033

782

18

0.0021

0.0141

NV4

257575

13102

301684

14964

366

0.0167

0.1625

NV5

219148

1043

220453

971

16

0.0002

0.0066

NV6

251356

3034

257134

2954

100

0.0027

0.0250

V1

224835

9705

262842

9398

234

0.0190

0.1607

V2

254176

15466

278062

17213

262

0.0097

0.0954

V3

308290

1327

417838

1302

49

0.0258

0.2913

V4

294426

5136

349308

5136

238

0.0105

0.1746

V5

259694

7373

274769

8288

176

0.0072

0.0610

V6

257651

1197

270071

1196

34

0.0070

0.0511

V7

259800

938

262788

900

32

0.0012

0.0126

V8

229324

1054

233338

1048

17

0.0025

0.0191

  1. a n_cln—number of unique CDR3β amino acid sequences
  2. b Number of clonotypes shared with the MIRA/Adaptive dataset
  3. c Fraction of repertoire’ sequences relative to S-specific clonotypes