Fig. 3

In vitro expansion of S-specific T cells. a Representative IFNγ-ELISPOT results for a case of NV and V COVID-19 patient. b Frequency of SFU of IFNγ-secreting cells following stimulation with the S-peptide pool in NV and V COVID-19 patient. *p = 0.003, **p = 0.006, Fisher’s test). Statistical comparison was performed by Kruskal–Wallis test. c, d Representative examples of tracking of the top 10 most abundant clonotypes from the post-stimulation repertoires of NV (c) and V (d) COVID-19 patients