Fig. 2

TCRβ repertoires diversity and clonality of COVID-19 and healthy groups. a For Gini-Simpson, D50 and Gini diversity significance see the Methods section. Statistical comparison was performed by Kruskal–Wallis test. b TCR repertoire fraction of the top 10, rare, and hyper-expanded clonotypes for all repertoires. Top 10 clonotype refers to the 10 most abundant clonotypes from each repertoire; rare and hyper-expanded refer to clonotype with a frequency less than 10^–5, or greater than 10^–2, respectively. The position of the value observed for the patient who experienced severe COVID-19 is highlighted in yellow. c Comparison of Vβ usage between V and NV COVID-19 groups. Statistical comparison was performed by Mann Whitney test