Fig. 14
From: Function and mechanism of GBP1 in the development and progression of cervical cancer
The CoIP-MS results of GBP1 in Caski cells. A The results of CoIP were verified by western blotting. Input group is the blank control group, showing background level, and IgG-IP group is the negative control. GAPDH was chosen as the internal reference. 70Â kDa is the estimated size of GBP1 molecule. B Silver staining was used to separate mixtures bound to GBP1. 1 and 2 represented two repeated experiments. C Venn diagram showing the overlapped and specific GBP1-interacted proteins between IP_1 and IP_2 samples. D Venn diagram showing the overlapped and specific GBP1-interacted proteins between IP and IgG samples. (187 GBP1-specific interacting proteins). E Bubble plot showing the top ten enriched GO BP pathways and KEGG pathways for GBP1 specific interacted proteins. F Network plot showing the relationship of proteins specific interacted with GBP1. CoIP-MS co-immunoprecipitation-mass spectroscopy, IP immunoprecipitation