Fig. 8
From: NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling
NCAPG2 is closely associated with PCa CSC characteristics. a Circos plot displaying the interconnectivity between NCAPG2 and stemness-related markers. b, c Representative images of sphere formation in PC3 and NCI-H660 cells and corresponding quantitative results. d, e Flow cytometry assay with CD44 in PCa cell lines and quantitative results. f-k The mRNA and protein expression of CSC makers (including ALDH1, SOX2, and EZH2) under the condition of NCAPG2 knockdown/upregulation in PC3 and NCI-H660 cells. PCa prostate cancer, CSC cancer stem cell. P values were calculated by the Student’s t-test. * means P < 0.05, ** means P < 0.01, *** means P < 0.001, and P < 0.05 is defined as statistically significant