Fig. 6

NCAPG2 could positively regulate the level of c-MYC. a WB showed that the expression of c-MYC was significantly suppressed following knockdown of NCAPG2, and NCAPG2 silencing could inhibit the effect of c-MYC overexpression plasmid in LNCaP and DU145 cells. b WB showed that the expression of c-MYC was significantly increased after NCAPG2 overexpression, and NCAPG2 upregulation could reverse the inhibitory effect of 10058-F4 in LNCaP and DU145 cells. WB western blot. P values were calculated by the Student’s t-test. * means P < 0.05, ** means P < 0.01, *** means P < 0.001, ns means P > 0.05, and P < 0.05 is defined as statistically significant