Fig. 1

NCAPG2 is highly expressed in PCa tissues and is a promising prognostic biomarker for PCa. a WB analysis validated that NCAPG2 protein was overexpressed in prostate tumors (T) compared to normal (N) benign prostate tissues. b Representative images of NCAPG2 IHC staining in para-carcinoma tissues and PCa tissues with different ISUP grades. c Statistical analysis of IHC assay showed that NCAPG2 expression in PCa tissues was significantly higher than that in adjacent tissues. d NCAPG2 expression increased with the pathological ISUP grades. e PFI survival analysis of the PCa patients with high- or low- NCAPG2 expression in TCGA database. f, g The tdROC indicated that the level of NCAPG2 could effectively predict the 1-year and 2-year PFI survival, respectively. PCa prostate cancer, WB western blot, IHC immunohistochemical staining, ISUP international Society of Urological Pathology, tdROC time-dependent receiver operating characteristic curve. * means P < 0.05, ** means P < 0.01, *** means P < 0.001, ns means P > 0.05, and P < 0.05 is defined as statistically significant