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Table 2 Level of fifteen different miRNAs with potent immunomodulatory actions

From: Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway

 

NP (n = 10) (mean ± SEM)

SM (n = 10) (mean ± SEM)

P Value

Has-miR-6087

1.287 ± 0.350

0.895 ± 0.529

0.544

Has-miR-451a

1.562 ± 0.344

1.780 ± 0.771

0.799

Has-miR-4492

1.155 ± 0.236

0.145 ± 0.037

0.001

Has-miR-3960

1.148 ± 0.215

0.476 ± 0.072

0.008

Has-miR-4488

1.240 ± 0.318

0.500 ± 0.105

0.040

Has-miR-144-3p

4.376 ± 2.443

4.492 ± 2.464

0.974

Has-miR-498-5p

1.421 ± 0.379

0.756 ± 0.515

0.312

Has-miR-512-3p

1.637 ± 0.482

1.196 ± 0.819

0.649

Has-miR-515-5p

1.819 ± 0.508

1.750 ± 1.144

0.956

Has-miR-541-3p

1.208 ± 0.257

0.226 ± 0.064

0.002

Has-miR-520 g-5p

1.228 ± 0.255

0.551 ± 0.320

0.116

Has-miR-592

2.433 ± 1.150

0.136 ± 0.047

0.061

Has-miR-410-5p

1.226 ± 0.335

0.090 ± 0.024

0.003

Has-miR-372-5p

1.918 ± 1.041

0.174 ± 0.043

0.112

Has-miR-541-5p

1.209 ± 0.252

0.272 ± 0.095

0.003

  1. NP normal pregnant, SM Spontaneous miscarriages
  2. The bold values represent the names and p-values of miRNAs that were statistically different in the NP and SM groups