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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma

Fig. 6

AIM2 upregulation correlates with a favorable response in cancer patients receiving immune checkpoint inhibitors. A Box plots for AIM2 mRNA levels in the non-responder (non-R) and responder (R) and receiver operating characteristic (ROC) curve (right) for the predictive sensitivity of AIM2 expression in ROC Plotter cancer patients receiving the indicated ICIs. B Kaplan–Meier analyses for AIM2 mRNA levels using progression-free survival probability under a maximal risk condition against K-M Plotter cancer patients receiving the indicated ICIs. C A proposed model for the AIM2-promoted radioresistance, metastasis and PD-L1 expression in refractory OSCC

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