Red blood cell-derived arginase release in hemolytic uremic syndrome

Table 3 Kidney histopathology in E. coli O157:H7-infected mice

Histopathological finding	E. coli O157:H7-infected (n = 9)	Controls (n = 4)
Tubular vacuolization	2 (0–2) ^a	1 (0–2)
Tubular epithelial desquamation	1.5 (0–3)	0 (0–0.5)
Interstitial edema	2 (0–2)	0.5 (0–1)

^a Scores represent median (range). For each mouse one entire kidney section was analyzed. Lesions were scored blindly as 0: absent, 1: mild, 2: moderate, or 3: severe

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