From: Recent advances of engineered oncolytic viruses-based combination therapy for liver cancer
Oncolytic virus | Viral structures | Critical pathway of specific infections in tumors | Partial genetically engineered oncolytic virus strains | References |
---|---|---|---|---|
Herpes simplex virus | Linear double-stranded DNA virus | Interferon signaling pathway | NV1020, G207, HF-10, HSV-1716, T-VEC, G47∆, M032, RP1, RP2, R36166, DM33, C134 | |
Newcastle disease virus | Single-stranded RNA virus | Interferon signaling pathway | Lasota, Anhinga, Mukteswar | |
Vaccinia virus | Linear double-stranded DNA virus | EGFR-Ras signaling pathway | Wyeth, Lister, Copenhagen, Western Reserve, Tian Tan, Modified, Vaccinia Ankar | |
Measles virus | Single-stranded RNA virus | Density differences of CD46, SLAM and Nectin-4 receptors | MV-CEA, MV-NIS | [39] |
Adenovirus | Linear double-stranded DNA virus | Rb and p53 cell signaling pathway | H101, ONYX-105, DNX-2401, LOAD703, VCN-01, OBP-301, ONCOS-102 |