Table 1 Correlations between has_circ_0050386 expression and clinical parameters among lung cancer patients
Clinical characteristics | Southern samples N (%) | Pa | Pb | Eastern samples N (%) | Pa | Pb | Total N (%) | Pa | Pb | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low expression | High expression | Low expression | High expression | Low expression | High expression | |||||||
Age | ||||||||||||
  < 60 | 45 (57.7) | 33 (42.3) | 0.593 | NA | 20 (62.5) | 12 (37.5) | 0.673 | NA | 65 (59.1) | 45 (40.9) | 0.844 | NA |
  ≥ 60 | 30 (62.5) | 18 (37.5) |  |  | 16 (57.1) | 12 (42.9) |  |  | 46 (60.5) | 30 (39.5) |  |  |
Gender | ||||||||||||
 Female | 51 (58) | 37 (42) | 0.585 | NA | 27 (62.8) | 16 (37.2) | 0.483 | NA | 78 (59.5) | 53 (40.5) | 0.954 | NA |
 Male | 24 (63.2) | 14 (36.8) |  |  | 9 (52.9) | 8 (47.1) |  |  | 33 (60) | 22 (40) |  |  |
Tumor family history | ||||||||||||
 No | 69 (61.6) | 43 (38.4) | 0.178 | 0.176 | 31 (57.4) | 23 (42.6) | 0.219 | 0.219 | 100 (60.2) | 66 (39.8) | 0.652 | 0.656 |
 Yes | 6 (42.9) | 8 (57.1) |  |  | 5 (83.3) | 1 (16.7) |  |  | 11 (55) | 9 (45) |  |  |
Smoking | ||||||||||||
 No | 27 (54) | 23 (46) | 0.306 | 0.133 | 10 (52.6) | 9 (47.4) | 0.428 | 0.425 | 37 (53.6) | 32 (46.4) | 0.196 | 0.166 |
 Yes | 48 (63.2) | 28 (36.8) |  |  | 26 (63.4) | 15 (36.6) |  |  | 74 (63.2) | 43 (36.8) |  |  |
Stages | ||||||||||||
 I + II | 22 (47.8) | 24 (52.2) | 0.043 | 0.047 | 9 (40.9) | 13 (59.1) | 0.022 | 0.023 | 31 (45.6) | 37 (54.4) | 0.003 | 0.003 |
 III + IV | 53 (66.3) | 27 (33.8) |  |  | 27 (71.1) | 11 (28.9) |  |  | 80 (67.8) | 38 (32.2) |  |  |
T status | ||||||||||||
 T1 + T2 | 36 (49.3) | 37 (50.7) | 0.006 | 0.007 | 13 (50) | 13 (50) | 0.167 | 0.168 | 49 (49.5) | 50 (50.5) | 0.003 | 0.003 |
 T3 + T4 | 39 (73.6) | 14 (26.4) |  |  | 23 (67.6) | 11 (32.4) |  |  | 62 (71.3) | 25 (28.7) |  |  |
N status | ||||||||||||
 N0 | 26 (60.5) | 17 (39.5) | 0.877 | 0.866 | 13 (48.1) | 14 (51.9) | 0.090 | 0.083 | 39 (55.7) | 31 (44.3) | 0.392 | 0.391 |
 N1 + N2 + N3 | 49 (59) | 34 (41) |  |  | 23 (69.7) | 10 (30.3) |  |  | 72 (62.1) | 44 (37.9) |  |  |
M status | ||||||||||||
 M0 | 47 (52.2) | 43 (47.8) | 0.008 | 0.010 | 20 (57.1) | 15 (42.9) | 0.593 | 0.555 | 67 (53.6) | 58 (46.4) | 0.016 | 0.016 |
 M1 | 28 (77.8) | 8 (22.2) |  |  | 16 (64) | 9 (36) |  |  | 44 (72.1) | 17 (27.9) |  |  |
Histological subtype | ||||||||||||
 Adenocarcinoma | 32 (52.5) | 29 (47.5) | 0.248 | 0.202 | 14 (56) | 11 (44) | 0.866 | 0.909 | 46 (53.5) | 40 (46.5) | 0.255 | 0.242 |
 Squamous carcinoma | 24 (63.2) | 14 (36.8) |  |  | 12 (63.2) | 7 (36.8) |  |  | 36 (63.2) | 21 (36.8) |  |  |
 Others | 19 (70.4) | 8 (29.6) |  |  | 10 (62.5) | 6 (37.5) |  |  | 29 (67.4) | 14 (32.6) |  |  |