Fig. 6

PIGT overexpression promotes cell growth, oxidative phosphorylation and glycolysis by activating GLUT1. BIU-87 cells were infected with control lentivirus (vector), PIGT overexpressing lentivirus (oePIGT) and/or GLUT1 shRNA lentivirus, and the (A) cell viability, (B) colony formation, (C) OCR, (D) ECAR, (E) lactic acid, (F) ATP levels and (G) GLUT1 expression were measured. * P < 0.05, *** P < 0.001 vs shNC + Vector. ^## P < 0.01, ^### P < 0.001 vs shNC + oePIGT