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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: PIGT promotes cell growth, glycolysis, and metastasis in bladder cancer by modulating GLUT1 glycosylation and membrane trafficking

Fig. 1

PIGT is clinically relevant in patients with bladder cancer. A UMAP plot of cell types in bladder cancer patients (PRJNA66201). B UMAP plot showing canonical marker genes for epithelial cells. C UMAP plot of tumor and normal tissue transcriptomes. D Gene expression of cancerous/normal cells by Volcano plot. E UMAP plot displayed the expression of PIGT. F Violin plot showed PIGT levels. G PIGT levels in cancer cells (T, red) and adjacent normal (N, blue) tissues in the TCGA database. H Survival analysis and comparison among people with high or low values of PIGT expression from TCGA database. I Results of PIGT expression in the hospital cohort (n = 25). J IHC staining of PIGT in bladder cancer microarrays. K Survival analysis and comparison among people with high or low PIGT in bladder cancer microarrays. ** P < 0.01, *** P < 0.001 vs normal (N)

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