Fig. 8
LTB4, but not 5-HETE, promoted migration and invasion of M2 macrophages. a Transwell pattern diagram. b Histogram showed the concentration of LTB4 in ICC-CM at an appropriate dilution. c Histogram showed the concentration of 5-HETE in ICC-CM at an appropriate dilution. d Transwell was used to detect the effect of different concentration gradients of LTB4 on the migration and invasion ability of M2 macrophages derived from THP-1. e Histogram showing the effect of different concentrations of LTB4 on the migration capacity of M2 macrophages derived from THP-1. f Histogram showing the effect of different concentrations of LTB4 on the invasion capacity of M2 macrophages derived from THP-1. g Transwell images showing the effect of different concentration gradients of 5-HETE on the migration and invasion ability of M2 macrophages derived from THP-1. h Histogram showing the effect of different concentrations of 5-HETE on the migration capacity of M2 macrophages derived from THP-1. i Histogram showing the effect of different concentrations of 5-HETE on the invasion capacity of M2 macrophages derived from THP-1. j Transwell was used to detect the effect of different concentration gradients of LTB4 on the migration and invasion ability of M2 macrophages derived from RAW264.7. k Histogram showing the effect of different concentrations of LTB4 on the migration capacity of M2 macrophages derived from RAW264.7. l Histogram showing the effect of different concentrations of LTB4 on the invasion capacity of M2 macrophages derived from RAW264.7. m Transwell images showing the effect of different concentration gradients of 5-HETE on the migration and invasion ability of M2 macrophages derived from RAW264.7. n Histogram showing the effect of different concentrations of 5-HETE on the migration capacity of M2 macrophages derived from RAW264.7. o Histogram showing the effect of different concentrations of 5-HETE on the invasion capacity of M2 macrophages derived from RAW264.7. (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)