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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway

Fig. 3

Bulk-RNA sequencing screened out lipid metabolism-related genes associated with TAM infiltration. (a) Differential expressed genes of 7 pairs of ICC tissues were displayed by heatmap. b Bubble diagram showing GO/KEGG enrichment analysis results. c Lollipop plots display the correlation of ALOX5 expression level with immune cells infiltration. d Scatter plot of correlation between ALOX5 expression level and macrophage infiltration abundance. e–g) Differences in macrophage infiltration scores between high and low ALOX5 expression groups were analyzed based on 3 different methods for evaluating immune infiltration. (*: P < 0.05, **: P < 0.01, ***: P < 0.001)

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Journal of Translational Medicine

ISSN: 1479-5876

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