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Fig.2 | Journal of Translational Medicine

Fig.2

From: ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway

Fig.2

Association between spatial localization of epithelial cells and TAMs. a Multiplex immunofluorescence staining was used to analyze the spatial distribution of TAM in dense and sparse areas of epithelial cells. (Markers: EPCAM: epithelial cells; CD68: macrophages; CD86: M1 macrophages; CD163: M2 macrophages) b Model diagram of multiplex immunofluorescence staining analysis of 12 ICC tissues. c Paired diagram of the number of M2 macrophages in dense and non-dense epithelial areas. (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)

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Journal of Translational Medicine

ISSN: 1479-5876

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