Fig. 7

miR-192 suppresses Rictor and inhibits hepatoma xenografts tumor growth in vivo. A Morphology of xenografts observed by the In-Vivo Xtreme Imaging System and the tumor growth curves of the indicated groups. Arrows indicate administration of 1 nmol of Chol-miR-192 (n = 6) or negative control (Chol-miR-NC, n = 6). B Quantitative analysis of Rictor and p21 expression via western blotting in resected tumors. C H&E staining and immunohistochemical staining of Rictor and Ki67 in representative xenograft tissue sections, quantified by densitometric analysis from five randomly selected high-power fields (magnification × 400) per slide (n = 6). D Schematic depicting the course of hepatocarcinogenesis and roles of established molecules during the process. *P < 0.05; ns no significant