Fig. 5

Translocation of Rictor in clinical patients with different TP53 mutation status. A, B Immunohistochemical (IHC) staining of p53 and Rictor in human HCC tissues harboring (A) wild-type TP53 and (B) mutant TP53. All background liver (BL) tissues exhibited wild-type TP53. Magnified regions are indicated by dashed boxes. C Differences in the cytoplasmic-nuclear distribution of Rictor are indicated by relative ratios of nuclear H-score to cytoplasmic H-score in HCC tissues with wild-type TP53 (n = 6) vs. mutant TP53 (n = 6). IHC staining: magnification × 400. **P < 0.01