Fig. 7

GSK-126 suppresses Gly-induced ferroptosis. A Tubular injury and CaOx crystal deposition were evaluated using H&E and Von-Kossa staining (n = 6). B Serum levels of BUN and Cr in different groups (n = 6). C Immunofluorescence analysis of SLC7A11, GPX4, and ACSL4 in kidney tissues (n = 6). D Western blotting analysis of SLC7A11, GPX4, ACSL4 and PTGS2 in kidney tissues. Scale bar = 50 μm. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the control group; ^#P < 0.05 and ^##P < 0.01 compared with the Gly group