Journal of Translational Medicine

Table 3 Myelin water fraction values in megalencephalic leukoencephalopathy with subcortical cysts 1 wild-type and knock-out mice according to predefined T₁ and T₂ values of myelin water

From: 3D MR fingerprinting-derived myelin water fraction characterizing brain development and leukodystrophy

	Combination		MLC1 WT mouse*		MLC1 KO mouse*
	T₁ (ms)	T₂ (ms)	Corpus callosum	Cortex	Corpus callosum	Cortex
Original	130	20	0.178	0.123	0.121	0.021
1	10	10	0.022	0.006	0.008	0
2	65	20	0.101	0.057	0.058	0.001
3	130	10	0.221	0.158	0.159	0.037
4	252	15	0.312	0.256	0.243	0.130
5	828	72	0.888	0.837	0.837	0.574

^* A 13-month-old mouse, MLC1 = megalencephalic leukoencephalopathy with subcortical cyst 1, WT = wild type, KO = knock-out

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ISSN: 1479-5876

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