Fig. 1

Flowchart of myelin water fraction (MWF) map generation using 3D MR fingerprinting (MRF). A 3D MRF acquisition scheme and reconstructed MRF images with a sinusoidal flip angle pattern and 3D stack-of-star acquisition trajectory (A). Signal evolutions of a partial volume dictionary for each component (myelin, intra/extracellular, and free water components) (B). Representative fraction maps of a mouse after dictionary matching (C). SVD, singular value decomposition