Skip to main content
Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation

Fig. 5

Network and functional analysis of ImmuneDEGs and MitoDEGs. Venn diagram showing 74 ImmuneDEGs (A) and 14 MitoDEGs (B). ImmuneDEGs and MitoDEGs were submitted to the STRING database and 10 hub ImmuneDEGs and 7 hub MitoDEGs were identified using the CytoHubba plugin in Cytoscape. Then, the 10 hub ImmuneDEGs (C) and 7 hub MitoDEGs (D) were uploaded in the GeneMANIA database for the further gene network analysis. The inner circle stands for hub genes, and the outer circle refers to the corresponding reciprocal genes. Colors of nodes represent gene function annotations, which refer to GO terms enriched among the genes in the network displayed by GeneMANIA. Colors of edges represent interaction based on co-expression, shared protein domain, co-localization, physical interactions, pathway, or predicted interaction. ImmuneDEGs, immune-related DEGs; MitoDEGs, mitochondria-related DEGs

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us