Fig. 1

Study flowchart. Two categories of samples (SARS-CoV-2 infected hiPSC-CMs and heart failure samples) were collected from the GSE156754 dataset and GSE84796 dataset, respectively. The common differentially expressed genes (DEGs) of both datasets were identified. GO enrichment analysis, KEGG pathway analysis, protein–protein interaction (PPI) network construction, hub genes identification, immune infiltration analysis, drug candidate prediction, and experimental validation were performed on the common DEGs. hiPSC-CMs, human induced pluripotent stem cell-derived cardiomyocytes