Fig. 1

Morphology and phenotype of SN-MM cell lines. Representative images of SN-MM cell lines are from a phase-contrast microscopy (A–E) or from cell-block sections of fixed cells (F–T) and stained as labelled. SN-MM cells display an epithelioid or spindle cell morphology with pleomorphic features (A–J) and strongly express Preferentially expressed Antigen in Melanoma (PRAME) (K–O) and SRY-box transcription factor 10 (SOX10) (P–T). Sections are counterstained with haematoxylin. Magnification 10X, scale bar 500 µm (A–E); magnification 400X, scale bar 50 µm (F-T)