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Fig. 9 | Journal of Translational Medicine

Fig. 9

From: Small-molecule agonist AdipoRon alleviates diabetic retinopathy through the AdipoR1/AMPK/EGR4 pathway

Fig. 9

a. The expression of cleaved-caspase 3 in the retina of DM and DMSO mice is significantly higher than that of the HFD group and reduced in the AdipoRon group, thereby indicating the alleviation of high-glucose-induced apoptosis after AdipoRon gavage. b. Strips quantified using Image J software. Statistical significance is indicated by ** p < 0.01. HFD, high-fat diet; DM, high-fat diet + diabetes mellitus control; DMSO, high-fat diet + diabetes mellitus + dimethyl sulfoxide negative control; AdipoRon, high-fat diet + diabetes mellitus + AdipoRon

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