Fig. 8

a. Altered AdipoR1 pathway-related proteins in the mouse retina. An increase in AMPK and ACC phosphorylation was noticed after AdipoRon treated.ACC and AMPKα remain unchanged, and the expression of p-AMPK and p-ACC is represented by p-AMPK/AMPKα and p-ACC/ACC. b: Strips quantified using Image J software are shown. The results are shown as mean ± standard deviation, **p < 0.01, ***p < 0.001. ACC, acetyl CoA carboxylase; AMPK, 5’ adenosine monophosphate-activated protein kinase; HFD, high-fat diet; DM, high-fat diet + diabetes mellitus control; DMSO, high-fat diet + diabetes mellitus + dimethyl sulfoxide negative control; AdipoRon, high-fat diet + diabetes mellitus + AdipoRon