Fig. 6

a. The reactive gliosis of Müller glia in each study group. GFAP staining of retinal cross sections (green) and nuclei counterstained with DAPI (blue) are shown. Here we can see vertically radial distribution after gliosis reactive,forming remarkable filamentous arrays in gliotic retina(DM,DMSO) b. Intensity of positive staining(green) quantity in retinal tissues of mice in four groups. Data are represented as the mean ± standard deviation *p < 0.05, **p < 0.01. RGC, retinal ganglion cell layer; INL inner nuclear layer, ONL outer nuclear layer, GFAP glial fibrillary acidic protein; DAPI, 4′,6-diamidino-2-phenylindole; HFD high-fat diet, DM high-fat diet + diabetes mellitus control; DMSO, high-fat diet + diabetes mellitus + dimethyl sulfoxide negative control; AdipoRon, high-fat diet + diabetes mellitus + AdipoRon