Fig. 4

a. RNA-binding protein with multiple splicing (RBPMS) staining (red) of the retinal flat mount in each group.After treated with AdipoRon, the number of RGCs recovered significantly, and the density was similar to that of the HFD group. b. Retinal ganglion cell (RGC) quantity in retinal tissues of mice in four groups. Data are represented as the mean ± standard deviation * p < 0.05. HFD, high-fat diet; DM, high-fat diet + diabetes mellitus control; DMSO, high-fat diet + diabetes mellitus + dimethyl sulfoxide negative control; AdipoRon, high-fat diet + diabetes mellitus + AdipoRon