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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Small-molecule agonist AdipoRon alleviates diabetic retinopathy through the AdipoR1/AMPK/EGR4 pathway

Fig. 3

Electroretinogram (ERG) change of four groups. ERG a-wave is shown on the left, and ERG b-wave is on the right.The stimulation intensity increased along the right gradient of the x-axis. The amplitude of the four intensity cut-off points is shown. The amplitudes of a-wave and b-wave of diabetic mice were decreased compared with HFD mice and AdipRon reversed the change under high stimulation (intensity 4).Data are represented as the mean ± standard deviation. *means of HFD vs. DM, p < 0.05; #means of AdipoRon vs. DM, p < 0.05. HFD, high-fat diet; DM, high-fat diet + diabetes mellitus control; DMSO, high-fat diet + diabetes mellitus + dimethyl sulfoxide negative control; AdipoRon, high-fat diet + diabetes mellitus + AdipoRon

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