Fig. 11

a. Oxidative stress levels in each group. The oxidative stress induced by high glucose was alleviated by AdipoRon, and the production of ROS rebounded after the AdipoR1-specific siRNA. b. ROS production can be decreased by AdipoRon, following which apoptosis improve. As with oxidative stress, the level of apoptosis increased again after the addition of AdipoR1-specific siRNA. The results are shown as mean ± standard deviation, *p < 0.05, **p < 0.01, ***p < 0.001. LG low glucose, HG high glucose