Fig. 2
From: Single protein encapsulated SN38 for tumor-targeting treatment
Properties of SPESN38-8 complex. A Particle size distribution profiles of SPESN38-8 and HSA, determined by DLS, indicating that SPESN38-8 and HSA had similar sizes. B SN38 release kinetics of different SN38 forms determined by membrane dialysis in 0.1Â M NaHCO3 buffer, pH 8.6. SN38 has very solubility in water. Therefore, its Na salt formed was used. Compared with relative to SN38 and SN38/HSA mixture, the slow dialysis kinetics of SPESN38-8 indicates non-covalent interactions between SN38 and HSA