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Table 2 Reclassification of the prediction model (4-miRNA combined CA-125) compared to CA-125 or 4-miRNA panel alone in subjects (n = 184)

From: Circulating small extracellular vesicles microRNAs plus CA-125 for treatment stratification in advanced ovarian cancer

Model

CA-125

CA-125 +  4-miRNA panel

P value

4-miRNA panel

4-miRNA panel + CA-125

P value

AUC

0.679

0.914

 < 0.0001

0.853

0.914

0.0007

NRI

0.471

 < 0.001

0.122

0.001

IDI

0.538

 < 0.001

0.185

0.003

  1. Significant P values in bold; IDI Integrated Discrimination Improvement, NRI net reclassification improvement
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Journal of Translational Medicine

ISSN: 1479-5876

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