Table 2 Comparison of key features of Tri©DB with those of other similar resources
From: Tri©DB: an integrated platform of knowledgebase and reporting system for cancer precision medicine
Database | Release time | Key knowledge domain | Primary presentation | Graphical presentation | Meta data | Pathway/interaction | Germline mutations | Immuno therapy | Cell therapy | Data access | Annotation report |
|---|---|---|---|---|---|---|---|---|---|---|---|
oncoKB | 2017 | Gene alterations, Therapies, Diseases, Brief interpretations | Tables, Texts | Lollipop graphs, Barcharts | Functional annotations, Population frequencies, Functional domains, Drug resistance | No | No | Yes | No | Browse, Search, API | Yes, license needed |
CIViC | 2017 | Gene alterations, Therapies, Diseases, Clinical trials, Assertive interpretations | Tables, Texts | / | Functional annotations, Population frequencies, Drug resistance, Literature references | No | No | Yes | No | Browse, Search, API, Download | No |
MCG | 2011 | Gene alterations, Therapies, Diseases, Clinical trials, Brief interpretations | Forms, Texts | Barchats, Pathway maps | Functional annotations, Population frequencies, Literature references | Yes | No | Yes | No | Browse, Search | No |
PMKB | 2017 | Gene alterations, Therapies, Diseases, Interpretations | Forms, Texts | / | Functional annotations, Drug resistance, External cross-links | No | No | No | No | Browse, Search, API | No |
CGI | 2018 | Gene alterations, Therapies, Diseases | Tables, Texts | / | Functional annotations, Drug resistance, External cross-links | No | No | No | No | Annotate, Filter, API, Download | No |
JAX-CKB | 2016 | Gene alterations, Therapies, Diseases, Clinical trials, Interpretations | Tables, Forms, Texts | / | Functional annotations, Drug resistance, External cross-links, Literature references | No | Not explicit | Yes | No | Partial access, license needed | No |
Tri©DB | 2022 | Gene alterations, Therapies, Diseases, Clinical trials, Recapitulative interpretations | Tables, Forms, Texts | Pathway maps, Interaction networks, Lollipop graphs, Barcharts | Functional annotations, Population frequencies, Functional domains, Drug resistance, Molecular structures, External cross-links, Literature references | Yes | Yes | Yes | Yes | Browse, Search, API, Download | Yes |