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Table 1 The annotatiaon attributes in the gene-, disease-, and therapy-oriented tabular views

From: Tri©DB: an integrated platform of knowledgebase and reporting system for cancer precision medicine

Attributes

Gene

Disease

Therapy

Gene

 + 

 + 

 + 

Alteration

 + 

 + 

 + 

Negative genotype

 + 

 + 

 + 

Disease

 + 

 + 

 + 

Drug name

 + 

 + 

 + 

Direct target

 + 

 + 

 + 

Specificity

 + 

 + 

 + 

Evidence level

 + 

 + 

 + 

Resistance

 + 

  

Clinical significance (ClinVar)

 + 

  

Clinical significance (COSMIC)

 + 

  

Clinical significance (VIC)

 + 

  

Variant classification

 + 

  

Carrier rate (GENIE)

 

 + 

 

Carrier rate (Chinese)

 

 + 

 

Carrier rate (Germline)

 

 + 

 

Drug type

  

 + 

Drug brand

  

 + 

Approval time

  

 +