Table 2 Anthropometric, biochemical, and histological characteristics of mice

Sex (female)

4 (50%)

4 (57.1%)

0.782

11 (61.1%)

7 (53.8%)

0.686

Body weight (g)

21.3 ± 2.61

18.9 ± 2.25

0.083

39.50 ± 7.38

28.06 ± 3.79

< 0.001***

Body length (cm)

8.65 ± 0.35

8.36 ± 0.42

0.160

9.27 ± 0.30

8.87 ± 0.32

< 0.001***

BMI (kg/m²)

28.38 ± 2.33

27.14 ± 2.61

0.351

45.82 ± 7.11

35.69 ± 3.40

< 0.001***

Total cholesterol (mg/dL)

141.50 ± 17.53

86.14 ± 10.75

< 0.001***

168.22 ± 43.45

85.69 ± 11.71

< 0.001***

HDL (mg/dL)

98.14 ± 13.93

59.43 ± 6.05

< 0.001***

111.78 ± 25.19

63.69 ± 11.88

< 0.001***

LDL (mg/dL)

82.03 ± 14.42

33.84 ± 9.48

< 0.001***

110.02 ± 36.82

36.61 ± 10.05

< 0.001***

Triglycerides (mg/dL)

110.00 ± 34.65

87.14 ± 24.31

0.089

74.33 ± 22.47

69.54 ± 15.93

0.516

AST (U/L)

83.60 ± 40.15

73.60 ± 28.04

0.660

247.44 ± 181.57

69.44 ± 20.40

0.008**

ALT (U/L)

57.18 ± 33.68

40.20 ± 29.61

0.092

67.35 ± 31.64

46.08 ± 35.41

0.047*

Glucose (mg/dL)

329.25 ± 26.00

307.71 ± 34.04

0.188

321.94 ± 79.11

271.00 ± 35.00

0.039*

Insulin (µU/mL)

1.33 ± 0.71

0.96 ± 0.25

0.219

2.79 ± 1.88

1.22 ± 0.30

0.042*

HOMA-IR

1.08 ± 0.57

0.73 ± 0.22

0.162

2.38 ± 1.78

0.87 ± 0.28

0.010**

Steatosis grade (0/1/2/3)

75%/25%/

0/0

100%/0/

0/0

0.155

5.6%/66.7%/

16.7%/11.1%

100%/0/0/0

< 0.001***

Lobular inflammation (0/1/2/3)

62.5%/25%/

12.5%/0

71.4%/28.6%/

0/0

0.626

27.8%/27.8%/

33.3%/11.1%

76.9%/23.1%/

0/0

0.022*

Ballooning (no/yes)

100%/0

100%/0

–

93.3%/6.7%

100%/0

–