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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation

Fig. 7

CoQ10@TNPs attenuated cardiac graft mitochondrial oxidative damage. A, B DHE staining was applied to evaluate the production of ROS in cardiac grafts. C The MDA level in cardiac grafts. D The activity of SOD in cardiac grafts. E The GSH level in cardiac grafts. F, G Immunofluorescence staining of 8-OHdg in cardiac grafts. H The level of protein carbonyl in cardiac grafts. I Undamaged mtDNA in the cardiac grafts. J Representative TEM images of mitochondria in cardiac grafts. Data are represented as the mean ± SD (n = 5). ns: no significance; *p < 0.05; **p < 0.01

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