Fig. 4From: Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantationCoQ10@TNPs reduced H9c2 cell apoptosis during cold I/R injury in vitro. A–C The level of cytochrome c in the cytoplasm and mitochondria. D, E The apoptosis rate of H9c2 cells was evaluated by FCM. F–I Western blotting was employed to evaluate the protein levels of Bax, Bcl-2, and C-caspase-3. Data are represented as the mean ± SD (n = 3). ns: no significance; *p < 0.05; **p < 0.01; ***p < 0.001Back to article page