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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation

Fig. 4

CoQ10@TNPs reduced H9c2 cell apoptosis during cold I/R injury in vitro. AC The level of cytochrome c in the cytoplasm and mitochondria. D, E The apoptosis rate of H9c2 cells was evaluated by FCM. FI Western blotting was employed to evaluate the protein levels of Bax, Bcl-2, and C-caspase-3. Data are represented as the mean ± SD (n = 3). ns: no significance; *p < 0.05; **p < 0.01; ***p < 0.001

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