Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation

Fig. 2

Characterization and intracellular trafficking of CoQ10@TNPs. A Diameter distribution of CoQ10@TNPs. B TEM morphology of CoQ10@TNPs. C Surface potential of CoQ10@TNPs. D The particle size of CoQ10@TNPs in ultrapure water. E The zeta potential of CoQ10@TNPs in ultrapure water. (F) CoQ10 release kinetics of CoQ10@TNPs. G Fluorescence microscopy images showing time-dependent cellular uptake of CoQ10@TNPs in H9c2 cells. H, I FCM analysis of the cellular uptake of CoQ10@TNPs in H9c2 cells after incubation for different periods. J, K Colocalization of mitochondria and CoQ10@TNPs in H9c2 cells. Data are represented as the mean ± SD (n = 3). ns: no significance; ***p < 0.001

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us