GATA6-AS1 suppresses epithelial–mesenchymal transition of pancreatic cancer under hypoxia through regulating SNAI1 mRNA stability

Table 1 Univariate and multivariate Cox regression analyses of overall survival in Cohort A of pancreatic cancer

Parameters	Univariate analysis, HR (95% CI)	P	Multivariate analysis, HR (95% CI)	P value
T stage
T3–T4 vs. T1–T2	1.98 (1.24–3.15)	0.004	1.86 (1.15–3.00)	0.011
N stage
N1 vs. N0	1.12 (0.66–1.92)	0.674
Tumor grade
G3 vs. G1 + G2	0.94 (0.60–1.47)	0.777
Tumor size, cm
≥ 4 vs. < 4	2.11 (1.33–3.36)	0.002	1.53 (0.94–2.50)	0.089
Vascular invasion
Yes vs. no	1.43 (0.45–4.57)	0.542
Adjuvant therapy
Yes vs. no	0.46 (0.28–0.75)	0.002	0.61 (0.37–1.01)	0.056
Neural invasion
Yes vs. no	2.34 (1.39–3.91)	0.001	2.35 (1.37–4.01)	0.002
GATA6-AS1 staining
High vs. low	0.43 (0.26–0.71)	0.001	0.66 (0.47–0.93)	0.018

Tumor classification and stage were referred to the 8th edition of UICC on cancer staging system
HR hazard ratio, CI confidence interval

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